ea0022p49 | Adrenal | ECE2010
Pivonello Claudia
, Napolitano Tiziana
, De Leo Monica
, Cozzolino Alessia
, Vitale Pasquale
, Lombardi Gaetano
, Colao Annamaria
, Pivonello Rosario
Somatostatin (SSTRs) and dopamine (DRs) receptors are expressed in adrenal tumors. It has been demonstrated in pituitary and neuroendocrine tumors that somatostatin-dopamine chimeric molecules, namely dopastatins, which bind both somatostatin (SST2 and/or SST5) and dopamine (D2) receptors, exert a more potent action compared with the single receptor agonists in experimental settings. The aims of this study were to evaluate the expression of DRs and SSTRs, and the effects of do...